منابع مشابه
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The possibility to replace damaged or diseased organs with arti®cial tissues engineered from a combination of living cells and biocompatible scaffolds is becoming a reality through multidisciplinary efforts. A number of critical components within this effort are being facilitated by microfabrication and MEMS approaches, including research tools to elucidate mechanisms which control cellular beh...
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Genome-modification technologies enable the rational engineering and perturbation of biological systems. Historically, these methods have been limited to gene insertions or mutations at random or at a few pre-defined locations across the genome. The handful of methods capable of targeted gene editing suffered from low efficiencies, significant labor costs, or both. Recent advances have dramatic...
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It is increasingly recognized that cell signaling, as a chemical process, must be considered at the local, micrometer scale. Micro- and nanofabrication techniques provide access to these dimensions, with the potential to capture and manipulate the spatial complexity of intracellular signaling in experimental models. This review focuses on recent advances in adapting surface engineering for use ...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2007
ISSN: 1940-087X
DOI: 10.3791/317